Dietary betaine reduces liver lipid accumulationviaimprovement of bile acid and trimethylamine-N-oxide metabolism in blunt-snout bream-Reference-Cited by-同舟云学术

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Dietary betaine reduces liver lipid accumulationviaimprovement of bile acid and trimethylamine-N-oxide metabolism in blunt-snout bream

Published:2019 Issue:10 Volume:10 Page:6675-6689
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Wang Fan¹²³⁴⁵,Xu Jia¹²³⁴⁵,Jakovlić Ivan⁶⁷⁸,Wang Wei-Min¹²³⁴⁵,Zhao Yu-Hua¹²³⁴⁵^ORCID

Affiliation:

1. College of Fisheries Huazhong Agricultural University

2. Key Lab of Freshwater Animal Breeding

3. Ministry of Agriculture

4. Key Lab of Agricultural Animal Genetics

5. Breeding and Reproduction of Ministry of Education

6. Bio-Transduction Lab

7. Wuhan 430075

8. PR China

Abstract

Dietary betaine decreased liver lipid accumulation caused by dietary carbohydrate through changes of TMA formation and TMAO and bile acid metabolism.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/FO/C9FO01853K

Reference76 articles.

1. Metabolite and gene expression profiles suggest a putative mechanism through which high dietary carbohydrates reduce the content of hepatic betaine in Megalobrama amblycephala

2. Transcriptomics, metabolomics and histology indicate that high-carbohydrate diet negatively affects the liver health of blunt snout bream (Megalobrama amblycephala)

3. Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives

4. Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor

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