Neuronal and glial cell co-culture organization and impedance spectroscopy on nanocolumnar TiN films for lab-on-a-chip devices

Author:

Abend Alice1,Steele Chelsie1,Schmidt Sabine2,Frank Ronny2,Jahnke Heinz-Georg2ORCID,Zink Mareike1ORCID

Affiliation:

1. Research Group Biotechnology and Biomedicine, Peter Debye Institute for Soft Matter Physics, Leipzig University, 04103 Leipzig, Germany

2. Centre for Biotechnology and Biomedicine, Molecular Biological-Biochemical Processing Technology, Leipzig University, 04103 Leipzig, Germany

Abstract

Co-cultured neuronal SH-SY5Y and U-87 MG cells grown with various ratios on TiN, TiN nano, and ITO exhibit distinct cellular organization, proliferation, and electrochemical impedance results depending on cell ratio and electrode material.

Funder

Sächsisches Staatsministerium für Wissenschaft und Kunst

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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