Copper-catalyzed arene amination in pure aqueous ammonia
Author:
Affiliation:
1. One-stop Sharing Facility Center for Future Drug Discoveries
2. Graduate School of Pharmaceutical Sciences
3. University of Tokyo
4. Tokyo
5. Japan
Abstract
A simple protocol for copper-catalyzed arene amination using aqueous ammonia without any additional ligands and organic coordinating solvents has been developed.
Funder
Takeda Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB02708K
Reference44 articles.
1. Transition-Metal-Catalyzed Monoarylation of Ammonia
2. Catalytic Organometallic Reactions of Ammonia
3. Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
4. Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides
5. Copper-mediated aromatic amination reaction and its application to the total synthesis of natural products
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