Multi-responsive polypeptide hydrogels derived from N-carboxyanhydride terpolymerizations for delivery of nonsteroidal anti-inflammatory drugs
Author:
Affiliation:
1. Departments of Chemistry
2. Chemical Engineering
3. Materials Science and Engineering
4. and Laboratory for Synthetic-Biologic Interactions
5. Taxes A&M University
Abstract
Multi-responsive polypeptide-based hydrogels exhibited thermo-, mechano-, and enzyme-responsive properties, enabling performance as a delivery system for encapsulation and release of naproxen.
Funder
National Heart, Lung, and Blood Institute
Division of Materials Research
Welch Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00931C
Reference56 articles.
1. Gastrointestinal Toxicity With Celecoxib vs Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis and Rheumatoid Arthritis
2. Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention Trial
3. d-Amino Acids Boost the Selectivity and Confer Supramolecular Hydrogels of a Nonsteroidal Anti-Inflammatory Drug (NSAID)
4. β-Amino Acid and Amino-Alcohol Conjugation of a Nonsteroidal Anti-Inflammatory Drug (NSAID) Imparts Hydrogelation Displaying Remarkable Biostability, Biocompatibility, and Anti-Inflammatory Properties
5. (S)-(+)-Ibuprofen-based hydrogelators: an approach toward anti-inflammatory drug delivery
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