On the prevalence of smooth polymorphs at the nanoscale: implications for pharmaceuticals
Author:
Affiliation:
1. Department of Chemistry
2. University of Cambridge
3. Cambridge CB2 1EW
4. UK
5. School of Chemical Engineering and Analytical Science
6. The University of Manchester
7. Manchester
8. Astra Zeneca
9. Department of Earth Sciences
Abstract
Ball mill neat grinding leads to smoother whereas liquid assisted grinding leads to rougher pharmaceutical forms.
Funder
Royal Society
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/CE/C8CE02098A
Reference52 articles.
1. Solvation and surface effects on polymorph stabilities at the nanoscale
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