Rhodium-catalyzed formal four-component reaction with hypervalent iodine diazoesters, alcohols, and isatins for the synthesis of multi-functionalized oxindoles

Author:

Tang Jie1,Yang Xiaoyan1,Niu Gejun1,Zhang Tianyuan1,Hu Wenhao1ORCID,Qian Yu1ORCID

Affiliation:

1. Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China

Abstract

A novel Rh(ii)-catalyzed formal four-component reaction involving hypervalent iodine diazoesters, alcohols, and isatins was effectively established as an efficient process to produce multi-functionalized oxindoles in good to high yields.

Funder

National Natural Science Foundation of China

Guangdong Provincial Key Laboratory of Construction Foundation

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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