Lipid-based colloidal nanoparticles for applications in targeted vaccine delivery

Author:

Khan Muhammad Saad12,Baskoy Sila Appak23,Yang Celina12,Hong Joohye4,Chae Jayoung4,Ha Heejin4,Lee Sungjun45,Tanaka Masayoshi6ORCID,Choi Yonghyun45,Choi Jonghoon45ORCID

Affiliation:

1. Department of Physics, Toronto Metropolitan University, 350 Victoria Street, Toronto, M5B2K3, Canada

2. Institute for Biomedical Engineering, Science and Technology (iBEST), St. Michael's Hospital, 209 Victoria Street, Toronto, M5B1W8, Canada

3. Department of Chemistry and Biology, Toronto Metropolitan University, Faculty of Science, 350 Victoria Street, Toronto, M5B2K3, ON, Canada

4. School of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea

5. Feynman Institute of Technology, Nanomedicine Corporation, Seoul 06974, Republic of Korea

6. Department of Chemical Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama-shi 226-8503, Kanagawa, Japan

Abstract

This review article demonstrated nucleic acid-based therapeutics and lipid nanoparticle type as a carrier of nucleic acid therapeutics for further applications of LNPs as flexible carriers in immuno-therapeutics and anti-cancer reagents.

Funder

Chung-Ang University

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Ministry of Environment

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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