Design, synthesis, spectroscopic characterization, computational analysis, and <i>in vitro</i> α-amylase and α-glucosidase evaluation of 3-aminopyridin-2(1<i>H</i>)-one based novel monothiooxamides and 1,3,4-thiadiazoles-Reference-Cited by-同舟云学术

Design, synthesis, spectroscopic characterization, computational analysis, and in vitro α-amylase and α-glucosidase evaluation of 3-aminopyridin-2(1H)-one based novel monothiooxamides and 1,3,4-thiadiazoles

Published:2022 Issue:45 Volume:20 Page:8962-8976
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Palamarchuk Irina V.¹^ORCID,Shulgau Zarina T.²^ORCID,Dautov Adilet Y.²,Sergazy Shynggys D.²,Kulakov Ivan V.¹^ORCID

Affiliation:

1. Tyumen State University, Institute of Chemistry, 15a Perekopskaya St., Tyumen 625003, Russia

2. National Center for Biotechnology, 13/5 Kurgalzhynskoe road, Nur-Sultan, 010000, Kazakhstan

Abstract

On the basis of biologically active 3-aminopyridin-2(1H)-ones, chemical modification of derivatives of the corresponding monothiooxamides, thiohydrazides, and conjugated 1,3,4-thiadiazole derivatives has been carried out for the first time.

Funder

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01772E

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