Nanodrug regulates lactic acid metabolism to reprogram the immunosuppressive tumor microenvironment for enhanced cancer immunotherapy-Reference-Cited by-同舟云学术

Nanodrug regulates lactic acid metabolism to reprogram the immunosuppressive tumor microenvironment for enhanced cancer immunotherapy

Published:2022 Issue:14 Volume:10 Page:3892-3900
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Tian Li-Rong¹,Lin Min-Zhao¹,Zhong Hui-Hai¹,Cai Yu-Jun¹^ORCID,Li Bo²,Xiao Ze-Cong³^ORCID,Shuai Xin-Tao¹²^ORCID

Affiliation:

1. PCFM Lab of Ministry of Education, School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou 510275, China

2. Nanomedicine Research Center, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China

3. Department of Minimally Invasive Interventional Radiology, and Laboratory of Interventional Radiology, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510275, China

Abstract

A novel strategy of tumor microenvironment reprogramming by Intra/extracellular lactic acid exhausting for antitumor immune therapy.

Funder

Key Technologies Research and Development Program of Guangzhou

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00650B

Reference40 articles.

1. The future of cancer immunotherapy: microenvironment-targeting combinations

2. Tumor Cell Metabolism: Cancer's Achilles' Heel

3. Nanodrug simultaneously regulates stromal extracellular matrix and glucose metabolism for effective immunotherapy against orthotopic pancreatic cancer

4. Recent advances in overcoming barriers to cell‐based delivery systems for cancer immunotherapy

5. How the Warburg effect supports aggressiveness and drug resistance of cancer cells?

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