Modelling protein therapeutic co-formulation and co-delivery with PLGA nanoparticles continuously manufactured by microfluidics-Reference-Cited by-同舟云学术

Modelling protein therapeutic co-formulation and co-delivery with PLGA nanoparticles continuously manufactured by microfluidics

Published:2020 Issue:2 Volume:5 Page:308-319
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Martins Cláudia¹²³⁴⁵,Chauhan Veeren M.⁶⁷⁸⁹¹⁰^ORCID,Selo Amjad A.⁶⁷⁸⁹¹⁰,Al-Natour Mohammad⁶⁷⁸⁹¹⁰,Aylott Jonathan W.⁶⁷⁸⁹¹⁰,Sarmento Bruno¹²³⁴⁵^ORCID

Affiliation:

1. i3S – Instituto de Investigação e Inovação em Saúde

2. Universidade do Porto

3. 4200-393 Porto

4. Portugal

5. INEB – Instituto de Engenharia Biomédica

6. School of Pharmacy

7. Boots Science Building

8. University of Nottingham

9. NG7 2RD Nottingham

10. UK

Abstract

Formulating protein therapeutics into nanoparticles (NPs) of poly(lactic-co-glycolic acid) (PLGA) provides key features such as protection against clearance, sustained release and less side effects by possible attachment of targeting ligands.

Funder

Fundação para a Ciência e a Tecnologia

European Regional Development Fund

Ministério da Ciência, Tecnologia e Ensino Superior

H2020 Marie Skłodowska-Curie Actions

Engineering and Physical Sciences Research Council

University of Nottingham

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RE/C9RE00395A

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