Screening of high-efficiency and low-toxicity antitumor active components in Macleaya cordata seeds based on the competitive effect of drugs on double targets by a new laminar flow chip

Author:

Gao Yan1234ORCID,Peng Huaidong5674,Li Lisi1234,Wang Feng12348,Meng Jiang1234,Huang Hongling9234,Wang Shumei834103,Li Paul C. H.123411,Sun Yue12348

Affiliation:

1. School of Traditional Chinese Medicine

2. Guangdong Pharmaceutical University

3. Guangzhou 510006

4. China

5. Department of Pharmacy

6. The Second Affiliated Hospital of Guangzhou Medical University

7. Guangzhou 510260

8. Engineering & Technology Research Center for Chinese Materia Medica Quality of Guangdong Province

9. School of Biosciences and Biopharmaceutics

10. Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of SATCM

11. Department of Chemistry

Abstract

An integrated technology for the competitive affinity of two targets using three-phase laminar flow chips. A method for rapid screening of active components with high efficiency and low toxicity from an extract of a traditional Chinese medicine.

Funder

Department of Education of Guangdong Province

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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