Remote drug loading into liposomes <i>via</i> click reaction-Reference-Cited by-同舟云学术

Remote drug loading into liposomes via click reaction

Published:2022 Issue:7 Volume:9 Page:1969-1977
ISSN:2051-6347
Container-title:Materials Horizons
language:en
Short-container-title:Mater. Horiz.

Author:

Zheng Yaxin¹^ORCID,Xie Lei¹,Tie Xiaoru¹,Cao Lei¹,Li Qingyuan¹,Quan Yue¹,Tang Lingfeng¹,Li Yang²^ORCID

Affiliation:

1. School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu, China

2. Department of Pharmaceutics, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, P. R. China

Abstract

We developed a click reaction-mediated active loading strategy, in which the drug loading was achieved by the generation of hydrophilic products in the liposome's lumen from the click reaction of glutathione with drug-maleimide conjugates.

Funder

Natural Science Foundation of Chongqing

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/MH/D2MH00380E

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4. Energy‐Free, Singlet Oxygen‐Based Chemodynamic Therapy for Selective Tumor Treatment without Dark Toxicity

5. Boosting the Ferroptotic Antitumor Efficacy via Site-Specific Amplification of Tailored Lipid Peroxidation

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