Surface topography of nanoplastics modulates their internalization and toxicity in liver cells

Author:

Yan Neng1ORCID,Wang Yuhuai1,Wong Tin Yan2ORCID,Hu Yubing3ORCID,Xu Huo4,Alessandro Parodi5ORCID,Pan Ke4ORCID,Liu Jingjing6ORCID,Lam Henry2,Tang Ben Zhong7,Shi Jianbo1ORCID

Affiliation:

1. State Environmental Protection Key Laboratory of Source Apportionment and Control of Aquatic Pollution, School of Environmental Studies, China University of Geosciences, Wuhan 430074, China

2. Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Kowloon, Hong Kong 999077, China

3. Department of Chemical Engineering, Imperial College London, London SW7 2BU, UK

4. SZU-HKUST Joint PhD Program in Marine Environmental Science, Shenzhen University, Shenzhen 518060, Guangdong Province, China

5. Scientific Center for Translation Medicine, Sirius University of Science and Technology, 354340 Sochi, Russia

6. Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China

7. Shenzhen Institute of Aggregate Science and Technology, School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China

Abstract

Though hepatotoxicity induced by the ubiquitous and potentially ingested nanoplastics (NPs) has been extensively studied, limited attention has been given to the role of NPs' surface topography.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hubei Province

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Environmental Science,Materials Science (miscellaneous)

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