Anti-inflammatory and gut microbiota modulatory effects of polysaccharides from Fuzhuan brick tea on colitis in mice induced by dextran sulfate sodium

Author:

Zeng Ziqi1,Xie Zhiyong1,Chen Guijie1ORCID,Sun Yi1,Zeng Xiaoxiong1ORCID,Liu Zhonghua23

Affiliation:

1. College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu, China

2. Key Laboratory of Ministry of Education for Tea Science, Hunan Agricultural University, Changsha 410128, China

3. National Research Center of Engineering Technology for Utilization of Botanical Functional Ingredients, Changsha 410128, China

Abstract

Crude polysaccharides from Fuzhuan brick tea (CFBTPS) and FBTPS-3 could promote the growth of beneficial bacteria, maintain the stability of the intestinal barrier and exhibit good anti-inflammatory activity against DSS-induced colitis in mice.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

National Key Research and Development Program of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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