Enzymatic reduction of acetophenone derivatives with a benzil reductase from Pichia glucozyma (KRED1-Pglu): electronic and steric effects on activity and enantioselectivity-Reference-Cited by-同舟云学术

Enzymatic reduction of acetophenone derivatives with a benzil reductase from Pichia glucozyma (KRED1-Pglu): electronic and steric effects on activity and enantioselectivity

Published:2016 Issue:13 Volume:14 Page:3404-3408
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Contente Martina L.¹²³⁴⁵,Serra Immacolata¹²³⁴⁵,Palazzolo Luca⁶³⁴⁵,Parravicini Chiara⁶³⁴⁵,Gianazza Elisabetta⁶³⁴⁵,Eberini Ivano⁶³⁴⁵,Pinto Andrea⁷³⁴⁵,Guidi Benedetta⁸³⁹⁵,Molinari Francesco¹²³⁴⁵,Romano Diego¹²³⁴⁵

Affiliation:

1. Department of Food

2. Nutritional and Environmental Sciences (DeFENS)

3. University of Milan

4. 20133 Milano

5. Italy

6. Department of Pharmacological and Biomolecular Sciences (DiSFeB)

7. Department of Pharmaceutical Sciences (DISFARM)

8. Department of Medical Biotechnology and Translational Medicine (BIOMETRA)

9. 20129 Milano

Abstract

Enantioselective reduction of mono-substituted acetophenones by ketoreductase KRED1-Pglu.