Synthesis of 2-alkyl-chroman-4-ones via cascade alkylation–dechlorination of 3-chlorochromones-Reference-Cited by-同舟云学术

Synthesis of 2-alkyl-chroman-4-ones via cascade alkylation–dechlorination of 3-chlorochromones

Published:2021 Issue: Volume: Page:
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Li Shunyao¹²³⁴⁵,Zhang Lanfei¹²³⁴⁵,He Qian¹²³⁴⁵,Zhang Xiaofei¹²³⁴⁵,Yang Chunhao¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Drug Research

2. Shanghai Institute of Materia Medica

3. Chinese Academy of Sciences

4. Shanghai 201203

5. China

Abstract

An efficient and mild synthetic approach for 2-alkyl-substituted chroman-4-ones via zinc mediated cascade decarboxylative β-alkylation and dechlorination of 3-chlorochromones was developed.

Funder

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

State Key Laboratory of Drug Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00463H

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