Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases-Reference-Cited by-同舟云学术

Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases

Published:2018 Issue:49 Volume:8 Page:28189-28197
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jiang Longguang¹²³⁴^ORCID,Zhang Xu⁵⁶⁷⁸⁴,Zhou Yang¹²³⁴,Chen Yayu¹²³⁴,Luo Zhipu⁹¹⁰¹¹¹²,Li Jinyu¹²³⁴^ORCID,Yuan Cai¹³²³⁴,Huang Mingdong¹²³⁴^ORCID

Affiliation:

1. College of Chemistry

2. Fuzhou University

3. Fuzhou 350116

4. China

5. Center for Life Science

6. School of Life Sciences

7. Yunnan University

8. Kunming 650021

9. Synchrotron Radiation Research Section

10. NCI

11. Argonne National Laboratory

12. USA

13. College of Biological Science and Engineering

Abstract

BrBA binds to the S1 pocket of urokinase with Br facing the base of the pocket by halogen bonds, while iodine of IBA binds to the S1 in the opposite way.

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA03145B

Reference59 articles.

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2. The Halogen Bond

3. The Nature and Geometry of Intermolecular Interactions between Halogens and Oxygen or Nitrogen

4. Prereactive Complexes of Dihalogens XY with Lewis Bases B in the Gas Phase: A Systematic Case for the Halogen Analogue B⋅⋅⋅XY of the Hydrogen Bond B⋅⋅⋅HX

5. Halogen Bonding—A Novel Interaction for Rational Drug Design?

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