Synthesis of methylphosphorylated oligomannosides structurally related to lipopolysaccharide O-antigens of <i>Klebsiella pneumoniae</i> serotype O3 and their application for detection of specific antibodies in rabbit and human sera-Reference-Cited by-同舟云学术

Synthesis of methylphosphorylated oligomannosides structurally related to lipopolysaccharide O-antigens of Klebsiella pneumoniae serotype O3 and their application for detection of specific antibodies in rabbit and human sera

Published:2023 Issue:41 Volume:21 Page:8306-8319
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Solovev Arsenii S.¹,Denisova Evgeniya M.²,Kurbatova Ekaterina A.¹³,Kutsevalova Olga Y.⁴,Boronina Liubov G.⁵,Ageevets Vladimir A.⁶,Sidorenko Sergey V.⁶,Krylov Vadim B.¹²^ORCID,Nifantiev Nikolay E.¹^ORCID

Affiliation:

1. Laboratory of Glycoconjugate Chemistry, N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russian Federation

2. Laboratory of Synthetic Glycovaccines, N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russian Federation

3. Laboratory of Immunology, I. I. Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia

4. National Medical Research Center of Oncology, Laboratory of Clinical Microbiology, 14 Liniya Str., 63, 344037 Rostov-on-Don, Russia

5. Ural State Medical University, 3 Repina Str., 620028 Yekaterinburg, Russia

6. Pediatric Research and Clinical Center for Infectious Diseases, 9 Prof. Popov Street, 197022 Saint Petersburg, Russia

Abstract

The synthesis and immunochemical application of spacer-armed oligosaccharides related to the outer fragment of the lipopolysaccharide of Klebsiella pneumoniae O3 are reported.

Funder

Ministry of Science and Higher Education of the Russian Federation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01203D

Reference34 articles.

1. Klebsiella pneumoniae: a major worldwide source and shuttle for antibiotic resistance

2. Antimicrobial resistance of gram-negative pathogens isolated from hospitalized patients in Rostov region

3. Modern problems of antibiotic resistance gram-negative nosocomial infections in the Rostov region

4. An integrated approach to the diagnosis of bacterial and fungal bloodstream infections in cancer patients

5. The Diversity of Lipopolysaccharide (O) and Capsular Polysaccharide (K) Antigens of Invasive Klebsiella pneumoniae in a Multi-Country Collection

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