Affiliation:
1. National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing 102206, China
Abstract
The direct arylation of optically pure 3,3′-difluoro-BINOL derivatives with (2,4,6-tri-tert-butylphenyl)magnesium bromide was developed to prepare highly hindered 3,3′-bis(2,4,6-tri-tert-butylphenyl)-BINOL-derived chiral phosphoric acids (CPAs).
Publisher
Royal Society of Chemistry (RSC)