Chemical synthesis of culmorin metabolites and their biologic role in culmorin and acetyl-culmorin treated wheat cells

Author:

Weber Julia123ORCID,Vaclavikova Marta45673,Wiesenberger Gerlinde8693ORCID,Haider Maximilian123ORCID,Hametner Christian123,Fröhlich Johannes123ORCID,Berthiller Franz45673ORCID,Adam Gerhard8693ORCID,Mikula Hannes123ORCID,Fruhmann Philipp1231011ORCID

Affiliation:

1. Institute of Applied Synthetic Chemistry

2. Vienna University of Technology (TU Wien)

3. Austria

4. Department of Agrobiotechnology (IFA-Tulln)

5. Center for Analytical Chemistry

6. University of Natural Resources and Life Sciences

7. Vienna (BOKU)

8. Department of Applied Genetics and Cell Biology

9. Tulln

10. Center for Electrochemical Surface Technology (CEST)

11. Wiener Neustadt

Abstract

An efficient procedure for the diastereo- and regioselective glucosylation of the mycotoxin culmorin (CUL) was developed. The synthesized glucosides and sulfates were used to investigate the CUL metabolism in wheat cells.

Funder

Österreichische Forschungsförderungsgesellschaft

Austrian Science Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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