Hepatitis B virus S gene therapy with 10-23 DNAzyme delivered by chitosan-g-stearic acid micelles-Reference-Cited by-同舟云学术

Hepatitis B virus S gene therapy with 10-23 DNAzyme delivered by chitosan-g-stearic acid micelles

Published:2019 Issue:27 Volume:9 Page:15196-15204
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Hong Yun¹²³⁴⁵,Mao Dongsen⁶⁷⁸⁹,Wu Rui¹⁰⁴¹¹⁹,Gao Zhe¹²³⁴⁵,Meng Tingting¹⁰⁴¹¹⁹,Wang Rongrong¹²³⁴⁵,Liu Lin¹²³⁴⁵,Miao Jing¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmacy

2. the First Affiliated Hospital

3. College of Medicine

4. Zhejiang University

5. Hangzhou 310003

6. Zhejiang Center of Laboratory Animals

7. Zhejiang Academy of Medical Sciences

8. Hangzhou 310007

9. P. R. China

10. College of Pharmaceutical Sciences

11. Hangzhou 310058

Abstract

DrzBS, which targets HBV S gene expression, has important research significance and potential application value. CSO-SA is a safe and efficient non-viral gene carrier and CSO-SA/DrzBS micelles are a promising application for anti-HBV gene therapy.

Funder

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA00330D

Reference46 articles.

1. World Health Organization , Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection , Geneva , 2015

2. Prevention of hepatitis B virus infection: from the past to the future

3. Epidemiology of Hepatocellular Carcinoma

4. Hepatitis B virus: virology, molecular biology, life cycle and intrahepatic spread

5. The natural history of chronic HBV infection and geographical differences

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