Investigation of the detoxification effect of licorice on Semen Strychni-induced acute toxicity in rats using a HPLC-Q-TOF/MS-based metabolomics approach-Reference-Cited by-同舟云学术

Investigation of the detoxification effect of licorice on Semen Strychni-induced acute toxicity in rats using a HPLC-Q-TOF/MS-based metabolomics approach

Published:2020 Issue:72 Volume:10 Page:44398-44407
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Xiang Yalan¹²³⁴⁵^ORCID,Wang Chao¹⁶⁷⁵^ORCID,Wen Jing¹²³⁴⁵^ORCID,Zhang Min¹²³⁴⁵^ORCID,Duan Xiaoyu¹²³⁴⁵^ORCID,Wang Lu¹²³⁴⁵^ORCID,Yan Miao¹²³⁴⁵,Li Huande¹²³⁴⁵^ORCID,Fang Pingfei¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmacy

2. The Second Xiangya Hospital

3. Central South University

4. Changsha 410011

5. China

6. Qingdao Municipal Hospital

7. Qingdao 266011

Abstract

Biomarkers and metabolomic pathway provide an integral understanding for the acute toxicity of Semen Strychni and the detoxification effect of licorice.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for Central Universities of the Central South University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA08568E

Reference34 articles.

1. Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica

2. Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity