Transition-metal-doped hydrophilic ultrasmall iron oxide modulates MRI contrast performance for accurate diagnosis of orthotopic prostate cancer-Reference-Cited by-同舟云学术

Transition-metal-doped hydrophilic ultrasmall iron oxide modulates MRI contrast performance for accurate diagnosis of orthotopic prostate cancer

Published:2022 Issue:46 Volume:10 Page:9613-9621
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Xie Wenteng¹²,Gan Yuehao¹²,Zhang Ya’nan³⁴,Wang Peng³⁴,Zhang Jia¹,Qian Junchao⁵,Zhang Guilong³⁴^ORCID,Wu Zhengyan¹^ORCID

Affiliation:

1. Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, P. R. China

2. University of Science and Technology of China, Hefei 230026, P. R. China

3. School of Pharmacy, Shandong Technology Innovation Center of Molecular Targeting and Intelligent Diagnosis and Treatment, Binzhou Medical University, Yantai 264003, P. R. China

4. Institute of Biomedical Imaging Probe, Binzhou Medical University, Yantai 264003, P. R. China

5. Hefei Cancer Hospital, Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, P. R. China

Abstract

This work clearly illustrated the mechanism of contrast enhancement in transition-metal-doped IONs, and it provides a novel paradigm for developing highly efficient T2 contrast agents.

Funder

National Natural Science Foundation of China

Major Science and Technology Projects in Anhui Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB01860H

Reference41 articles.

1. Octapod iron oxide nanoparticles as high-performance T2 contrast agents for magnetic resonance imaging

2. Magnetic nanoparticles in MR imaging and drug delivery