The discovery of new phloroglucinol glycosides from Agrimonia pilosa and the mechanism of oxidative dearomatization of the methyl-substituted phloroglucinol derivatives-Reference-Cited by-同舟云学术

The discovery of new phloroglucinol glycosides from Agrimonia pilosa and the mechanism of oxidative dearomatization of the methyl-substituted phloroglucinol derivatives

Published:2021 Issue:36 Volume:11 Page:22273-22277
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Jia¹²³⁴⁵,Yang Ya-Nan¹²³⁴⁵^ORCID,Jiang Jian-Shuang¹²³⁴⁵,Feng Zi-Ming¹²³⁴⁵,Yuan Xiang¹²³⁴⁵,Zhang Xu¹²³⁴⁵,Zhang Pei-Cheng¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines

2. Institute of Materia Medica

3. Peking Union Medical College

4. Chinese Academy of Medical Sciences

5. Beijing 100050

Abstract

New phloroglucinol glycosides, aglycones, and oxidative dearomatized products of aglycones were discovered from Agrimonia pilosa, and the mechanism of the auto oxidative dearomatization was disclosed as a free radical chain reaction with ³O₂.

Funder

Chinese Academy of Medical Sciences Initiative for Innovative Medicine

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA03588F

Reference22 articles.

1. Phenolic glycosides from Agrimonia pilosa

2. Acylphloroglucinolated Catechin and Phenylethyl Isocoumarin Derivatives from Agrimonia pilosa

3. Ellagitannin and flavonoid constituents from Agrimonia pilosa Ledeb. with their protein tyrosine phosphatase and acetylcholinesterase inhibitory activities

4. Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis

5. Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis

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