A microfluidic-chip-based system with loop-mediated isothermal amplification for rapid and parallel detection of Trichomonas vaginalis and human papillomavirus

Author:

Mao Zeyin1ORCID,Deng Anni1ORCID,Jin Xiangyu1ORCID,Li Meng2,Lv Wenqi1,Huang Leyang1,Zhong Hao1,Yang Han1,Wang Shihong1,Shi Yixuan1,Zhang Lei2,Liao Qinping2,Huang Guoliang13

Affiliation:

1. Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China

2. Department of Obstetrics and Gynecology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China

3. National Engineering Research Center for Beijing Biochip Technology, Beijing 102206, China

Abstract

A microfluidic-chip system is developed using LAMP for fast and simultaneous detection of Trichomonas vaginalis and high-risk human papillomavirus, and it is promisingly applicable in various fields, particularly in co-infection diagnosis.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Sichuan Province Science and Technology Support Program

Tsinghua University

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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