A regioselective C7 bromination and C7 palladium-catalyzed Suzuki–Miyaura cross-coupling arylation of 4-substituted NH-free indazoles-Reference-Cited by-同舟云学术

A regioselective C7 bromination and C7 palladium-catalyzed Suzuki–Miyaura cross-coupling arylation of 4-substituted NH-free indazoles

Published:2021 Issue:12 Volume:11 Page:7107-7114
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Boujdi Khalid¹²³⁴⁵,El Brahmi Nabil¹²³⁴⁵,Graton Jérôme⁶⁷⁸⁹¹⁰^ORCID,Dubreuil Didier⁶⁷⁸⁹¹⁰,Collet Sylvain⁶⁷⁸⁹¹⁰,Mathé-Allainmat Monique⁶⁷⁸⁹¹⁰,Akssira Mohamed¹¹¹²¹³¹⁴⁵,Lebreton Jacques⁶⁷⁸⁹¹⁰,El Kazzouli Saïd¹²³⁴⁵^ORCID

Affiliation:

1. Euromed Research Center

2. School of Engineering in Biomedical and Biotechnology

3. Euromed University of Fes (UEMF)

4. 30000 Fez

5. Morocco

6. Laboratoire CEISAM–UMR 6230

7. Université de Nantes

8. CNRS

9. Faculté des Sciences et des Techniques

10. 44322 Nantes Cedex 3

11. Faculty of Sciences and Technologies Mohammedia

12. University Hassan 2

13. URAC 22 FSTM University Hassan II – Casablanca

14. 28800 Mohammedia

Abstract

A regioselective C7-bromination of 4-substituted 1H-indazoles followed by a palladium-catalyzed Suzuki–Miyaura reaction with boronic acids is described.

Funder

Centre National pour la Recherche Scientifique et Technique

Université de Nantes

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA08598G

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2. Design, Synthesis and Biological Evaluation of Pazopanib Derivatives as Antitumor Agents