Bacterial siderophore mimicking iron complexes as DNA targeting antimicrobials

Author:

Boda Sunil Kumar1234,Pandit Subhendu1234,Garai Aditya5234,Pal Debnath6234,Basu Bikramjit12347

Affiliation:

1. Laboratory for Biomaterials – Materials Research Centre

2. Indian Institute of Science

3. Bangalore – 560012

4. India

5. Department of Inorganic and Physical Chemistry

6. Department of Computational and Data Sciences

7. Centre for Biosystems Science and Engineering

Abstract

Microbial secretion of siderophores for iron uptake can be employed as an efficient strategy to smuggle in bactericidal agents by conjugation to iron.

Funder

Department of Biotechnology , Ministry of Science and Technology

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference44 articles.

1. Bacteria, iron and pathogenicity

2. A. Symeonidis and M.Marangos, Iron and Microbial Growth, Insight and Control of Infectious Disease in Global Scenario, 2012, ISBN 978-953-51-0319-6

3. Bacterial iron homeostasis

4. Iron acquisition by Gram-positive bacterial pathogens

5. Siderophore-mediated iron acquisition in the staphylococci

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