Selective halocyclization and iodosulfonylation of N-benzothiazol-2-yl alkynamides under mild conditions

Author:

Fang Yu1,Ren Shangfeng1,He Chen2,Han Huiqi2,Liu Jin-Biao1ORCID,Liao Fumin1,Yang Min2ORCID

Affiliation:

1. Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, Ganzhou 341000, China

2. Key Laboratory of Biomaterials and Biofabrication in Tissue Engineering of Jiangxi Province, Key Laboratory of Biomedical Sensors of Ganzhou, School of Pharmacy, School of Basic Medicine, Gannan Medical University, Ganzhou, 341000, China

Abstract

The selective halocyclization and iodosulfonylation of N-benzothiazol-2-yl alkynamides under mild conditions is described, affording pyrimidobenzothiazoles and multisubstituted α,β-enones respectively.

Funder

Science Fund for Distinguished Young Scholars of Jiangxi Province

Education Department of Jiangxi Province

Gannan Medical University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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