Dual-channel NIR activatable theranostic prodrug for in vivo spatiotemporal tracking thiol-triggered chemotherapy-Reference-Cited by-同舟云学术

Dual-channel NIR activatable theranostic prodrug for in vivo spatiotemporal tracking thiol-triggered chemotherapy

Published:2016 Issue:8 Volume:7 Page:4958-4965
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ye Mingzhou¹²³⁴⁵,Wang Xiaohang⁶⁷⁸⁹¹⁰,Tang Jianbin¹²³⁴⁵,Guo Zhiqian⁶⁷⁸⁹¹⁰,Shen Youqing¹²³⁴⁵,Tian He⁶⁷⁸⁹¹⁰,Zhu Wei-Hong⁶⁷⁸⁹¹⁰

Affiliation:

1. Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Center for Bionanoengineering

2. College of Chemical and Biological Engineering

3. Zhejiang University

4. Hangzhou

5. P. R. China

6. Key Laboratory for Advanced Materials and Institute of Fine Chemicals

7. Shanghai Key Laboratory of Functional Materials Chemistry

8. School of Chemistry and Molecular Engineering

9. East China University of Science and Technology

10. Shanghai 200237

Abstract

Real-time tracking of where, when, and how prodrugs are established. A novel theranostic prodrug based on the disulfide linkage with two distinct switchable near-infrared (NIR) fluorescence can precisely extract the prodrug release profilein vivothrough dual-channel fluorescent imaging for the first time.

Funder

Fok Ying Tong Education Foundation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C6SC00970K

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