Enantioselective synthesis of quaternary 3,4-dihydroisoquinolinonesviaHeck carbonylation reactions: development and application to the synthesis of Minalrestat analogues-Reference-Cited by-同舟云学术

Enantioselective synthesis of quaternary 3,4-dihydroisoquinolinonesviaHeck carbonylation reactions: development and application to the synthesis of Minalrestat analogues

Published:2019 Issue:42 Volume:10 Page:9853-9858
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Cheng Cang¹²³⁴⁵,Wan Bin¹²³⁴⁵,Zhou Bo¹²³⁴⁵^ORCID,Gu Yichao¹²³⁴⁵,Zhang Yanghui¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemical Science and Engineering

2. Shanghai Key Laboratory of Chemical Assessment and Sustainability

3. Tongji University

4. Shanghai 200092

5. China

Abstract

A Pd-catalyzed enantioselective intramolecular carbonylative Heck reaction has been developed by using formate esters as the source of CO.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC03406D

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4. Novel Spirosuccinimide Aldose Reductase Inhibitors Derived from Isoquinoline-1,3-diones: 2-[(4-Bromo-2-fluorophenyl)methyl]-6-fluorospiro[isoquinoline-4(11H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and Congeners. 1

5. N-Substituted Spirosuccinimide, Spiropyridazine, Spiroazetidine, and Acetic Acid Aldose Reductase Inhibitors Derived from Isoquinoline-1,3-diones. 2

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