Novel oxaliplatin(<scp>iv</scp>) complexes conjugated with ligands bearing pendant 1,2-dithiolane/1,2-diselenolane/cyclopentyl motifs-Reference-Cited by-同舟云学术

Novel oxaliplatin(iv) complexes conjugated with ligands bearing pendant 1,2-dithiolane/1,2-diselenolane/cyclopentyl motifs

Published:2022 Issue:44 Volume:51 Page:16824-16835
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Liu Xiao¹^ORCID,Wenisch Dominik²^ORCID,Barth Marie-Christin¹,Cseh Klaudia²^ORCID,Kowol Christian R.²^ORCID,Jakupec Michael A.²^ORCID,Gibson Dan³^ORCID,Keppler Bernhard K.²^ORCID,Weigand Wolfgang¹^ORCID

Affiliation:

1. Institute of Inorganic and Analytical Chemistry, Friedrich Schiller Universität Jena, Humboldt Str. 8, 07743 Jena, Germany

2. Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Strasse 42, 1090 Vienna, Austria

3. Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, 91120 Israel

Abstract

Using isologous 1,2-dithiolane, 1,2-diselenolane and cyclopentyl containing analogues as axial ligands, three series of oxaliplatin(iv) complexes were synthesized. The effects of ligands on cytotoxicity profile were investigated.

Funder

Erasmus+

China Scholarship Council

Israel Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/DT/D2DT02217F

Reference70 articles.

1. The status of platinum anticancer drugs in the clinic and in clinical trials