A novel TMTP1-modified theranostic nanoplatform for targeted in vivo NIR-II fluorescence imaging-guided chemotherapy for cervical cancer

Author:

Alifu Nuernisha1ORCID,Ma Rong2,Zhu Lijun1,Du Zhong2,Chen Shuang2,Yan Ting1,Alimu Gulinigaer1,Zhang Linxue1,Zhang Xueliang1

Affiliation:

1. State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia School of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, 830011, China

2. State Key Laboratory of Pathogenesis, Prevention, and Treatment of High Incidence Diseases in Central Asia, Department of Gynecology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China

Abstract

A novel IR-783-DOX-TMTP1 theranostic nanoplatform with strong targeting ability was prepared and used for in vivo NIR-II fluorescence imaging of intratumoral vessels and chemotherapy of cervical tumor-bearing mice.

Funder

National Natural Science Foundation of China

Department of Education, Xinjiang Uygur Autonomous Region

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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