Native chemical ligation in protein synthesis and semi-synthesis
Author:
Affiliation:
1. Faculty of Chemistry
2. Institute of Biological Chemistry
3. University of Vienna
4. Vienna
5. Austria
6. School of Chemistry
7. The University of Sydney
8. Sydney
9. Australia
Abstract
Combining modern synthetic and molecular biology toolkits, native chemical ligation and expressed protein ligation enables robust access to modified proteins.
Funder
Australian Research Council
Vienna Science and Technology Fund
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CS/C8CS00573G
Reference50 articles.
1. Synthesis of Proteins by Native Chemical Ligation
2. Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins
3. Rapid and efficient protein synthesis through expansion of the native chemical ligation concept
4. Free-Radical-Based, Specific Desulfurization of Cysteine: A Powerful Advance in the Synthesis of Polypeptides and Glycopolypeptides
5. Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology
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