Synthesis, structural characterization and cytotoxicity of a new proton transfer compound based on 2,4-diamino-1,3,5-triazine: an experimental and computational study-Reference-Cited by-同舟云学术

Synthesis, structural characterization and cytotoxicity of a new proton transfer compound based on 2,4-diamino-1,3,5-triazine: an experimental and computational study

Published:2021 Issue:42 Volume:45 Page:19755-19763
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Gholivand Khodayar¹^ORCID,Babaee Leila Sarmadi¹^ORCID,Fallah Nasrin²^ORCID,Faraghi Mohammad¹^ORCID,Dusek Michal³^ORCID,Eigner Vaclav³^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Sciences, Tarbiat Modares University, Tehran, Iran

2. Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran

3. Institute of Physics ASCR, Na Slovance 2, 182 21 Prague 8, Czech Republic

Abstract

A water-soluble proton transfer compound was synthesized and characterized. Non-covalent interactions were studied by X-ray crystallography and DFT calculations. Anticancer activities were investigated and supported by a molecular docking study.

Funder

Ministerstvo Školství, Mládeže a Tělovýchovy

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ03674B

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