Responsive upconversion nanoprobe for monitoring and inhibition of EBV-associated cancersviatargeting EBNA1

Author:

Zha Shuai1234ORCID,Fung Yan Ho1234ORCID,Chau Ho-Fai12345,Ma Ping'an67894,Lin Jun67894ORCID,Wang Jing1011121314ORCID,Chan Lai Sheung5234,Zhu Guang151634ORCID,Lung Hong Lok5234ORCID,Wong Ka-Leung1234ORCID

Affiliation:

1. Department of Chemistry

2. Hong Kong Baptist University

3. Kowloon

4. P. R. China

5. Department of Biology

6. State Key Laboratory of Rare Earth Resource Utilization

7. Changchun Institute of Applied Chemistry

8. Chinese Academy of Sciences

9. Changchun

10. Ministry of Education Key Laboratory of Bioinorganic and Synthetic Chemistry

11. State Key Laboratory of Optoelectronic Materials and Technologies

12. School of Chemistry

13. Sun Yat-Sen University

14. Guangzhou

15. Division of Life Science

16. Hong Kong University of Science and Technology

Abstract

Responsive emission enhancement was observed between EBNA1 and dual-function EBNA1-targeting nanoprobe UCNP-P4, monitoring and inhibition of EBV-associated tumor is achieved.

Funder

Hong Kong Baptist University

Research Grants Council, University Grants Committee

National Natural Science Foundation of China

CAS-Croucher Funding Scheme for Joint Laboratories

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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