Amide synthesis via nickel-catalysed reductive aminocarbonylation of aryl halides with nitroarenes

Author:

Cheung Chi Wai12345,Leendert Ploeger Marten12345,Hu Xile12345ORCID

Affiliation:

1. Laboratory of Inorganic Synthesis and Catalysis

2. Institute of Chemical Sciences and Engineering

3. Ecole Polytechnique Fédérale de Lausanne (EPFL)

4. ISIC-LSCI

5. Lausanne 1015

Abstract

A nickel-catalysed reductive aminocarbonylation of (hetero)aryl halides employing readily available nitro(hetero)arenes as the nitrogen source has been developed.

Funder

École Polytechnique Fédérale de Lausanne

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference38 articles.

1. The Amide Linkage: Structural Significance in Chemistry, Biochemistry, and Materials Science , ed. A. Greenberg , C. M. Breneman and J. F. Liebman , Wiley-Interscience , Chichester, New York , 2000

2. Metal-catalyzed amidation

3. Rethinking amide bond synthesis

4. Nonclassical Routes for Amide Bond Formation

5. Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals

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