Intelligent Janus nanoparticles for intracellular real-time monitoring of dual drug release

Author:

Cao Han1234,Yang Yuhong534,Chen Xin1234,Shao Zhengzhong1234

Affiliation:

1. State Key Laboratory of Molecular Engineering of Polymers

2. Department of Macromolecular Science and Laboratory of Advanced Materials

3. Fudan University

4. Shanghai, P. R. China

5. Research Center for Analysis and Measurement

Abstract

A novel nanosystem, Janus particle Dox-CMR-MS/Au-6MP with opposing mesoporous silica and gold faces is able to monitor intracellular dual-drug responsive release in real time based on fluorescence resonance energy transfer (FRET) and surface-enhanced Raman scattering (SERS).

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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