Protonated montmorillonite-mediated highly specific isomerization of oleanolic acid esters: application to the synthesis of Δ13(18)-CDDO-Me-Reference-Cited by-同舟云学术

Protonated montmorillonite-mediated highly specific isomerization of oleanolic acid esters: application to the synthesis of Δ13(18)-CDDO-Me

Published:2016 Issue:47 Volume:14 Page:11154-11161
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Chen Dongyin¹²³⁴⁵,Zhang Pu¹²³⁴,Sun Yan¹²³⁴,Wang Pengfei¹²³⁴,Zhang Can¹²³⁴,Kong Lingyi¹²³⁴,Zhang Ji⁶²³⁴,Sun Hongbin¹²³⁴,Wen Xiaoan¹²³⁴

Affiliation:

1. Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease and State Key Laboratory of Natural Medicines

2. China Pharmaceutical University

3. Nanjing 210009

4. China

5. Department of Medicinal Chemistry

6. Department of Physical Chemistry

Abstract

A one-pot highly specific isomerization of oleanolic acid esters (5a–g) to δ-oleanolic acid esters (6a–g) was achieved in the presence of proton-exchanged montmorillonite (H-mont) under mild reaction conditions.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB02126C

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