Influence of pH and Mg(ii) on the catalytic core domain 5 of a bacterial group II intron

Author:

Pechlaner M.1234,Dominguez-Martin A.1234ORCID,Sigel R. K. O.1234

Affiliation:

1. Department of Chemistry

2. University of Zurich

3. Zurich

4. Switzerland

Abstract

The combination of NMR and fluorescence spectroscopy was used to elucidate how Mg(ii) and pH influence the local conformation and metal ion binding in domain 5 ofAzotobacter vinelandiigroup II intron.

Funder

Swiss National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Reference37 articles.

1. Group II Introns: Structure and Catalytic Versatility of Large Natural Ribozymes

2. Structural and Catalytic Roles of Metal Ions in RNA in Metal Ions in Life Science (MILS), ed. A. Sigel, H. Sigel and R. K. O. Sigel, Springer International Publishing, Cambridge, 2011, vol. 9

3. A Second Divalent Metal Ion in the Group II Intron Reaction Center

4. Crystal Structure of a Self-Spliced Group II Intron

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