Mapping the metabolic characteristics of probiotic-fermented Ganoderma lucidum and its protective mechanism against Cd-induced nephrotoxicity

Author:

Dai Zhen123,Li Gaoheng2,Wang Xixi2,Gao Bo2,Gao Xiuwei2,Strappe Padraig4,Zhou Zhongkai125ORCID

Affiliation:

1. Key Laboratory for Processing and Quality Safety Control of Characteristic Agricultural Products, the Ministry of Agriculture and Rural Affairs, Shihezi University, Shihezi 832003, China

2. College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China

3. State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, China

4. School of Medical and Applied Sciences, Central Queensland University, Rockhampton, Qld 4700, Australia

5. Gulbali Institute-Agriculture Water Environment, Charles Sturt University, Wagga Wagga, NSW 2678, Australia

Abstract

An animal model of Cd-induced kidney damage was designed to investigate the nephroprotective potential of the probiotic-fermented Ganoderma lucidum (FGL) via metabonomic analysis.

Funder

Natural Science Foundation of Tianjin City

High-end Foreign Experts Recruitment Plan of China

National Major Science and Technology Projects of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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