Photosensitizer–peptoid conjugates for photoinactivation of Gram-negative bacteria: structure–activity relationship and mechanistic studies

Author:

Yang Woojin1234,Yoon Younggun5234,Lee Yunjee1234,Oh Hyeongyeol1234ORCID,Choi Jieun1234,Shin Sujin5234ORCID,Lee Seongsoo6784,Lee Hohjai1234ORCID,Lee Yunho5234ORCID,Seo Jiwon1234ORCID

Affiliation:

1. Department of Chemistry

2. Gwangju Institute of Science and Technology

3. Gwangju 61005

4. South Korea

5. School of Earth Sciences and Environmental Engineering

6. Gwangju Center

7. Korea Basic Science Institute (KBSI)

8. Gwangju 61751

Abstract

A library of peptoid-based antimicrobial photodynamic therapy (aPDT) agents was prepared, and the structural requirement for efficient aPDT was disclosed.

Funder

National Research Foundation of Korea

Korea Basic Science Institute

Gwangju Institute of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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