Advances in the chemical and biological diversity of heterocyclic systems incorporating pyrimido[1,6-a]pyrimidine and pyrimido[1,6-c]pyrimidine scaffolds-Reference-Cited by-同舟云学术

Advances in the chemical and biological diversity of heterocyclic systems incorporating pyrimido[1,6-a]pyrimidine and pyrimido[1,6-c]pyrimidine scaffolds

Published:2020 Issue:26 Volume:10 Page:15461-15492
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Elattar Khaled M.¹²³⁴⁵^ORCID,Mert Başak Doğru⁶⁷⁸⁹,Monier M.¹²³⁴⁵,El-Mekabaty Ahmed¹²³⁴⁵^ORCID

Affiliation:

1. Chemistry Department

2. Faculty of Science

3. Mansoura University

4. Mansoura

5. Egypt

6. Adana Alparslan Türkeş Science and Technology University

7. Department of Energy Systems Engineering

8. Adana

9. Turkey

Abstract

The current study provides an overview of the synthetic routes, reactivity and privileged biological characteristics of bicyclic heterocycles incorporating pyrimido[1,6-a]pyrimidine and pyrimido[1,6-c]pyrimidine cores.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA00411A

Reference109 articles.

1. Biological Evaluation of Pyrimidopyrimidines as Multi-Targeted Small Molecule Inhibitors and Resistance Modifying Agents

2. Inhibition of Epidermal Growth Factor Receptor Activity by Two Pyrimidopyrimidine Derivatives

3. Inhibition of ferrous-induced lipid peroxidation by pyrimido-pyrimidine derivatives in human liver membranes

4. Synthesis of quaternised 2-aminopyrimido[4,5-d]pyrimidin-4(3H)-ones and their biological activity with dihydrofolate reductase

5. Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes

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