A polyphosphoester-conjugated camptothecin prodrug with disulfide linkage for potent reduction-triggered drug delivery
Author:
Affiliation:
1. College of Chemistry
2. Chemical Engineering and Materials Science
3. Suzhou Key Laboratory of Macromolecular Design and Precision Synthesis
4. Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application
5. Soochow University
Abstract
A reduction-cleavable polyphosphoester-camptothecin (CPT) prodrug tailored for enhancing drug loading content and triggering drug release has been prepared and applied in tumor chemotherapy.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2015/TB/C5TB00623F
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