Synthesis of pyrazolo[1,5-a]quinoxalin-4(5H)-ones via one-pot amidation/N-arylation reactions under transition metal-free conditions-Reference-Cited by-同舟云学术

Synthesis of pyrazolo[1,5-a]quinoxalin-4(5H)-ones via one-pot amidation/N-arylation reactions under transition metal-free conditions

Published:2016 Issue:37 Volume:14 Page:8721-8727
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wiethan Carson¹²³⁴,Franceschini Steffany Z.¹²³⁴,Bonacorso Helio G.¹²³⁴,Stradiotto Mark⁵⁶⁷⁸

Affiliation:

1. Departamento de Química

2. Universidade Federal de Santa Maria

3. 97105-900 Santa Maria

4. Brazil

5. Department of Chemistry

6. Dalhousie University

7. Halifax

8. B3H 4R2 Canada

Abstract

An efficient one-pot procedure for the synthesis of new pyrazolo[1,5-a]quinoxalin-4(5H)-ones from easily prepared 1-(2-chlorophenyl-5-ethylcarboxylate)pyrazoles and various primary alkylamines is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01407K

Reference20 articles.

1. A. R. Katritzky , C. A.Ramsden, E. F. V.Scriven and R. J. K.Taylor, Comprehensive Heterocyclic Chemistry III, Pergamon, Oxford, 2008

2. A. Ricci , Amino Group Chemistry: From Synthesis to the Life Sciences, Wiley-VCH, Weinheim, 2008

3. C–N bond forming cross-coupling reactions: an overview

4. Dialkylbiaryl phosphines in Pd-catalyzed amination: a user's guide

5. Diversification of edaravone via palladium-catalyzed hydrazine cross-coupling: Applications against protein misfolding and oligomerization of beta-amyloid

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Regiocontrolled Synthesis of 1-Substituted-3(5)-carboxyalkyl-1H-pyrazoles Using Trichloromethyl Enones;ACS Omega;2023-05-04

2. Transition metal-free cross-coupling reactions to form carbon–heteroatom bonds;Russian Chemical Reviews;2022-07-01

3. Copper-Catalyzed Oxidative [3 + 2]-Annulation of Quinoxalin-2(1H)-one with Oxime Esters toward Functionalized Pyrazolo[1,5-a]quinoxalin-4(5H)-ones as Opioid Receptor Modulators;The Journal of Organic Chemistry;2022-05-19

4. Novel 7-(1H-pyrrol-1-yl)spiro[chromeno[4,3-b]quinoline-6,1′-cycloalkanes]: synthesis, cross-coupling reactions, and photophysical properties;New Journal of Chemistry;2021

5. Generation of aryl radicals by redox processes. Recent progress in the arylation methodology;Russian Chemical Reviews;2021-01-01