1. Department of Cardiology
2. Zhujiang Hospital of Southern Medical University
3. Guangzhou 510280, P. R. China
4. State Key Laboratory of Medicinal Chemical Biology
5. Key Laboratory of Bioactive Materials
6. Ministry of Education
7. and College of Life Sciences
8. Collaborative Innovation Center of Chemical Science and Engineering
9. College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Design
10. Nankai University
11. Tianjin 300071, P. R. China