Artificial spinal dura mater made of gelatin microfibers and bioadhesive for preventing cerebrospinal fluid leakage

Author:

Sun Shengdong12,Luo Hao3,Wang Yuanfei14,Xi Yongming3,Fang Kuanjun1256,Wu Tong1237ORCID

Affiliation:

1. Shandong Key Laboratory of Medical and Health Textile Materials, College of Textiles and Clothing, Qingdao University, Qingdao, 266071, China

2. Collaborative Innovation Center for Eco-Textiles of Shandong Province and the Ministry of Education, Qingdao University, Qingdao, 266071, China

3. Affiliated Hospital of Qingdao University, Qingdao Medical College, Qingdao University, Qingdao, 266071, China

4. Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, 266001, China

5. Laboratory for Manufacturing Low Carbon and Functionalized Textiles in the Universities of Shandong Province, Qingdao, 266071, China

6. State Key Laboratory for Biofibers and Eco-textiles, 308 Ningxia Road, Qingdao 266071, China

7. Institute of Neuroregeneration & Neurorehabilitation, Department of Pathophysiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China

Abstract

Artificial spinal dura mater was designed by combining solution blow-spun gelatin microfibers and dopamine-capped polyurethane bioadhesive.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Key Technology Research and Development Program of Shandong Province

China Association for Science and Technology

Taishan Scholar Project of Shandong Province

State Key Laboratory of Bio-Fibers and Eco-Textiles

Publisher

Royal Society of Chemistry (RSC)

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