Synthesis of 3-amino-substituted benzothiadiazine oxides by a palladium-catalysed cascade reaction

Author:

Hommelsheim Renè1ORCID,Bausch Sandra1,van Nahl Robin1,Ward Jas S.2ORCID,Rissanen Kari2ORCID,Bolm Carsten1ORCID

Affiliation:

1. Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany

2. University of Jyvaskyla, Department of Chemistry, FI-40014 Jyväskylä, Finland

Abstract

By using a very low catalyst loading, a wide range of cyclic sulfoximine derivatives, that represent common cores of bioactive products, can be prepared in good to excellent yields at room temperature in a short period of time.

Funder

Fonds der Chemischen Industrie

Friedrich-Ebert-Stiftung

Alexander von Humboldt-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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