Metal- and photocatalyst-free three-component strategy to prepare benzylalcohol-, aldehyde-substituted BCP building blocks-Reference-Cited by-同舟云学术

Metal- and photocatalyst-free three-component strategy to prepare benzylalcohol-, aldehyde-substituted BCP building blocks

Published:2024 Issue:9 Volume:26 Page:5531-5537
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Li Fei¹,Liao Huijuan¹,Dong Jianyang¹,Xiong Weikang¹,Yan Yonggang¹^ORCID,Li Gang¹^ORCID,Xue Dong¹^ORCID

Affiliation:

1. Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, China

Abstract

A mild one-step, light-promoted, three-component radical-coupling reaction of [1.1.1]propellane to afford difunctionalized benzylalcohol-, aldehyde-substituted BCPs in the absence of metals, photocatalysts or external oxidants was reported.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shaanxi Province

Fundamental Research Funds for the Central Universities

Higher Education Discipline Innovation Project

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/GC/D4GC01015A

Reference62 articles.

1. Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

2. Improving Nonspecific Binding and Solubility: Bicycloalkyl Groups and Cubanes as para -Phenyl Bioisosteres

3. Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor

4. Conquering the Synthesis and Functionalization of Bicyclo[1.1.1]pentanes

5. Applications of Bioisosteres in the Design of Biologically Active Compounds

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1. Site-Specific Radical Alkylation of Aryl Cyanide: Visible-Light, Photoredox-Catalyzed, Three-Component Arylalkylation of [1.1.1]Propellane;Organic Letters;2024-09-04

2. Photoinduced Multicomponent Heteroarylation of [1.1.1]Propellane with Katritzky Pyridinium Salts;Organic Letters;2024-08-14

3. Transition-metal-, oxidant- and additive-free multi-component synthesis of alkyl heteroaryl BCPs enabled by visible-light-induced phosphine-catalyzed halogen-atom transfer;Organic Chemistry Frontiers;2024