Fighting fire with fire: remodeling Aβ aggregation with H-aggregates of a europium(<scp>iii</scp>) complex-Reference-Cited by-同舟云学术

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Fighting fire with fire: remodeling Aβ aggregation with H-aggregates of a europium(iii) complex

Published:2024 Issue: Volume: Page:
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Zhou Yuancun¹,Zhu Jiacheng¹,Gao Furong¹,Hu Ming¹,Qian Chengyuan²,Wang Xin¹,Wang Xiaohui¹^ORCID

Affiliation:

1. Institute of Chemical Biology and Functional Molecules, State Key Laboratory of Materials-Oriented Chemical Engineering, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, P. R. China

2. School of Life Sciences, Nanjing University, Nanjing 210093, P. R. China

Abstract

A “Fight Aggregation with Aggregation” approach for redirection of Aβ aggregation by using the H-aggregates of a europium(iii) complex to remodel Aβ oligomers into non-fibrillar co-assemblies.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D4DT02188F

Reference30 articles.

1. Alzheimer disease

2. Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases

3. The Cellular Phase of Alzheimer’s Disease

4. A vicious cycle of β amyloid–dependent neuronal hyperactivation

5. Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

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