End-functionalised glycopolymers as glycosaminoglycan mimetics inhibit HeLa cell proliferation-Reference-Cited by-同舟云学术

End-functionalised glycopolymers as glycosaminoglycan mimetics inhibit HeLa cell proliferation

Published:2020 Issue:29 Volume:11 Page:4714-4722
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Yang Chendong¹²³⁴⁵,Gao Lei¹²³⁴⁵,Shao Meng¹²³⁴⁵,Cai Chao¹²³⁴⁵^ORCID,Wang Lihao¹²³⁴⁵,Chen Yifan¹²³⁴⁵,Li Jianghua¹²³⁴⁵,Fan Fei¹²³⁴⁵,Han Yubing¹²³⁴⁵,Liu Ming¹²³⁴⁵,Linhardt Robert J.⁶⁷⁸⁹¹⁰^ORCID,Yu Guangli¹²³⁴⁵

Affiliation:

1. Key Laboratory of Marine Drugs

2. Ministry of Education & Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology

3. School of Medicine and Pharmacy

4. Ocean University of China

5. Qingdao 266003

6. Department of Chemistry and Chemical Biology

7. Center for Biotechnology and Interdisciplinary Studies

8. Rensselaer Polytechnic Institute

9. Troy

10. USA

Abstract

A novel glycopeptide mimetic, prepared by end-functionalised conjugation of iRGD peptide on a glycopolymer, could effectively enter HeLa cells and inhibit signalling pathways involved in tumour cell proliferation.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/PY/D0PY00384K

Reference52 articles.

1. Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans